Dog

Panoquell for Dogs

PANOQUELL -CA1 (fuzapladib sodium injection) is the first FDA conditionally approved treatment for the management of clinical signs associated with acute onset of pancreatitis in dogs.

A fast, safe and effective treatment for the management of the inflammation associated with acute canine pancreatitis (ACP) LFA-1 activation inhibitor Inhibits the infiltration of neutrophilic inflammation within the pancreas Given once daily for 3 consecutive days by IV bolus injection Proven to quickly reduce clinical signs and measurable values such as canine pancreas-specific lipase (Spec cpL) and C-reactive protein (CRP) associated with ACP With the multi-use vial, there is the ability to treat multiple patients and there is a reduction in waste Can be given in conjunction with other supportive care treatments For intravenous use in dogs only Can reduce time and stress often seen in the hospital setting with ACP treatment

Possible Side Effects

In the pilot field effectiveness study, PANOQUELL-CA1 was administered safely with other supportive care treatments including anti-emetics and pain control. The most common adverse reactions included anorexia, digestive tract disorders, respiratory tract disorders and hepatopathy and jaundice.

Recommended Dosage

Use as directed by you veterinarian. 

PANOQUELL-CA1 is 4 mg/mL solution when reconstituted. It comes in a multi-use vial. Once reconstituted, it remains stable under refrigeration for 28 days.

PANOQUELL-CA1 consists of two separate vials.

One vial contains 14 mg of fuzapladib sodium, 52.5 mg of D-mannitol, and 21 mg of tromethamine as sterile lyophilized powder. The second vial of 3.9 mL sterile diluent (bacteriostatic water for injection), containing 1.8% w/v benzyl alcohol, is for reconstituting the sterile lyophilized powder prior to use.

No other diluent should be used.

PANOQUELL-CA1 is an intravenous (IV) injection dosed once a day for 3 days. The IV injection can be given over 15 seconds to 1 minute as a bolus.

Storage Instructions

Store unopened vials at room temperature, 59° to 77°F (15° to 25°C).

Store the reconstituted product at refrigerated conditions, 36° to 46°F (2° to 8°C). Use within 28 days of first puncture.

FAQs

1. What is Panoquell-CA1 used for?                                                                        Panoquell-CA1 is used to manage and treat acute pancreatitis in dogs by reducing inflammation and managing pain. 

2. How is Panoquell-CA1 administered?                                                                Panoquell-CA1 for dogs is administered via injection. The powder must be reconstituted with a suitable diluent to achieve the proper concentration (4mg/mL), and the dosage should be determined by a veterinarian.

3. Is Panoquell-CA1 safe for all dogs?                                                                    The medication is generally safe when used as directed by a veterinarian. It is specifically designed for dogs with acute pancreatitis. Always consult with a veterinarian before starting treatment.

4. How often should Panoquell-CA1 be administered?                                        The frequency and dosage of Panoquell-CA1 administration depend on the severity of the dog's condition and the veterinarian's recommendation.

5. Can Panoquell-CA1 be used for long-term treatment?                            Panoquell-CA1 is typically used as an acute pancreatitis treatment for dogs. The duration of treatment should be determined by a veterinarian based on the dog's response and recovery.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.